The Power of Microbicides:

Advancing follow-on rings




Expanding the range of woman-centered and long-acting microbicides could open up a new era in women’s sexual and reproductive health. Dapivirine ring research has demonstrated the potential for a vaginal ring to effectively reduce women’s HIV risk—and the interest that many women have in self-initiated, long-acting prevention methods.


IPM is building on its pioneering monthly ring technology with longer-acting products: a three-month dapivirine ring and a three-month dapivirine-contraceptive ring that could simultaneously prevent HIV and unintended pregnancy. Data analysis from Phase I trials for both rings was underway in 2019, but was subsequently delayed by the COVID-19 pandemic in 2020. Results from both trials are now expected by early 2021.